# How to accelerate the demultiplex speed?
**URL:** https://community.artic.network/t/how-to-accelerate-the-demultiplex-speed/42
**Category:** Bioinformatics
**Created:** [27 March 2020 00:36 UTC](https://community.artic.network/t/how-to-accelerate-the-demultiplex-speed/42 "2020-03-27T00:36:27Z")
**Posts on this page:** 4
**Page:** 1
### Author:  [@indexofire](https://community.artic.network/u/indexofire)
#### Post date: [27 March 2020 00:36 UTC](https://community.artic.network/t/how-to-accelerate-the-demultiplex-speed/42/1 "2020-03-27T00:36:27Z")
ARTIC tools use porechop to re-demultiplexing the samples obligatorily. However it take too much time in my SERVER like 8G fastq per day. Anyway to accelerate the process?
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### Author:  [@nick](https://community.artic.network/u/nick)
#### Post date: [27 March 2020 18:19 UTC](https://community.artic.network/t/how-to-accelerate-the-demultiplex-speed/42/2 "2020-03-27T18:19:51Z")
We have also noticed similar problems with slow demultiplexing, particularly when very large files are used as Porechop will read the entire file into memory.
We are considering moving shortly to Guppy demultiplexing (needs --require\_barcodes\_both\_ends set) being prepared, this seems to work faster. This will likely be the default option in a new version of the pipeline, scheduled for release in the next day or two.
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### Author:  [@nick](https://community.artic.network/u/nick)
#### Post date: [29 March 2020 20:12 UTC](https://community.artic.network/t/how-to-accelerate-the-demultiplex-speed/42/3 "2020-03-29T20:12:30Z")
The instructions for demultiplexing via Guppy can now be found at:
[https://artic.network/ncov-2019/ncov2019-bioinformatics-sop.html](https://artic.network/ncov-2019/ncov2019-bioinformatics-sop.html)
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### Author:  [@indexofire](https://community.artic.network/u/indexofire)
#### Post date: [30 March 2020 03:30 UTC](https://community.artic.network/t/how-to-accelerate-the-demultiplex-speed/42/4 "2020-03-30T03:30:57Z")
Thank you, Nick! Update so quickly, I will try ASAP.